DNA-Based Active Logic Design and Its Implications

DNA computing is an emerging field of research in which biochemistry and molecular biology elements are utilized to complete computational processes performed by traditional silicon-based technologies. Current DNA-based circuits are nonhomogenous, consisting of discrete combinatorial gates with corresponding static processing abilities. This research focuses on further developing DNA-based methodologies to mimic digital data manipulation. Homogenous logic design principles are introduced, laying the foundations of dynamic processing whereby information can be parsed through a digital circuit comprised of DNA–based logic gates. The ultimate aim would be to facilitate shift-and-add calculation. More immediate applications concern data tamper-proofing, serving security needs whose progress was previously limited. A novel logic gate design based on chemical reactions is presented in which observance of double stranded sequences indicates a truth evaluation. Circuits are obfuscated by removing of physical sequence connections, allowing client-specific representative strands for input sequences, altering the input sequence strands over time, and varying the input sequence length.